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Large numbers of peroxisomes containing D-amino acid oxidase and catalase are localized in the S 3 portion of the proximal tubule, but they are absent from the glomerulus and the distal nephron

[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Beckman J.S., Koppenol W.H

Dementia 2023;22(4):854874

The most common adverse effects from the SURMOUNT trials include: Nausea: 24-33% of participants (dose-dependent) Diarrhea: 18-25% of participants Constipation: 13-17% of participants Vomiting: 8-12% of participants Decreased appetite: 10-15% of participants Most of these effects are mild to moderate and occur primarily during dose escalation periods

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