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The main objective of this review is to focus on the different aspects of HNE-induced cell death, with a particular emphasis on apoptosis

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The renin-angiotensin system (RAS) is a paracrine RAS within the central nervous system (CNS) and is closely related to Alzheimers disease (AD)

Furthermore, we investigate potential therapeutic strategies targeting oxidative stress and DNA repair mechanisms, focusing on antioxidant approaches, gene editing technologies, and pharmacological interventions to mitigate oxidative damage