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Both studies employed essentially identical designs and recruited patients with a history of migraine with or without aura (of at least 6 months in duration) who were experiencing at least 2 migraine headaches a month during the 3 months prior to enrollment

Fixed drug eruptions are more commonly seen in people with dark skin and often present as a slate brown color due to pigmentary incontinence of melanophages in the upper dermis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Bibbins-Domingo K, et al

Consequently, we suggest that nhr-49 plays a prominent role in promoting the breakdown of fatty acids in mitochondria, and that, through control of -oxidation, nhr-49 influences overall fat storage