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210 Acetyl-CoA then starts the TCA cycle, where NAD + serves as a coenzyme for three rate-limiting enzymes, -ketoglutarate dehydrogenase (KGDH), isocitrate dehydrogenase 3 (IDH3) and malate dehydrogenase (MDH2), to generate NADH
GBD 2017 Causes of Death Collaborators

10.1186/s13046-018-0950-9 70 LiuJ.XueH.ZhangJ.SuoT.XiangY.ZhangW.et al

As discussed above, ruminants only get B12 deficient if they are Co deficient
Unfortunately, it is often taken without medical guidance, leading to misuse

Additionally, glycine inhibits proteolytic gene expression, which is a technical way of saying it reduces the signals that tell your body to break down muscle proteins for energy
