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Berberine and cisplatin exhibit synergistic anticancer effects on osteosarcoma MG-63 cells by inhibiting the MAPK pathway

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reported that curcumin encapsulated in RGD peptide-PEGylated nanoliposomes derived from salmon lecithin exhibits improved stability, neuronal compatibility, and neuroprotective efficacy

KEAP1 has highly reactive thiol groups that act as a sensor for the NRF2 inducers.4 The cysteine residue (Cys151) in the KEAP1-BTB domain is essential for NRF2 activation,5 while Cys288 and Cys297 are crucial for the suppression of NRF2 activity.6 The Kelch domain of KEAP1 mediates the binding of the Neh2 domain to NRF2 and thereby negatively regulates NRF2 transactivation

Purified L-theanine is available as an oral dietary supplement, and is used for its perceived antioxidant and relaxant effects (12)

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