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Ratanesh Kumar Seth, University of South Carolina, United States Updates Copyright 2021 Labarrere and Kassab

CFPAC-1 and SW1990 cell lines were transfected with shVRK2 plasmids, and PANC-1 and BxPC-3 cell lines were transfected with VRK2-overexpressing plasmids by applying Lipofectamine 3000 reagent according to the manufacturers protocol

FIGURE 2 3.1 Subcellular dysfunction and oxidative stress 3.1.1 Mitochondria and oxidative stress Mitochondrial dysfunction plays a critical role in the pathogenesis of BIPN

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Weight management : Older people have a reduced ability to produce glutathione naturally, which can lead to a reduced ability to burn fat, as well as weight gain

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