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In conclusion, IL-8 as a CXC chemokine produced by various cell types is well-known as a potent angiogenic factor through paracrine and autocrine routes in tumorigenesis

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In the other groups, ASD was administered intragastrically at a single dose of 100 mg/kg in a saline solution (0.9% NaCl) (Group B), in a saline solution (0.9% NaCl) of 50% vegetable oil (Groups C), to rats pretreated with metronidazole (2500 mg/kg, i