glutathione biosynthesis pathway SYNTHESIS Glutathione Metabolism - an overview
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GSTs have emerged as a promising therapeutic target because specific isozymes are overexpressed in a wide variety of tumors and may play a role in the etiology of other diseases, including neurodegenerative diseases, multiple sclerosis, and asthma

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Lets say that your target protein is smaller than GST, such that most of the size of the GST-fusion protein will be contributed from GST and not your target protein
Glutamine is an amino acid that supports muscle growth and immune function, while glutathione is a powerful antioxidant that helps protect cells from oxidative stress