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Tomorrow will be my first week on semaglutide, and honestly it has been an incredible change
Absorption of isotopically labelled 5-formyl-THF across the colon at a considerably lower rate (about one-fiftieth) than across the small intestine has been reported

If someone has soreness and pain at the injection site, then pain killers such as paracetamol or ibuprofen can be given if suitable
As well as causing B12 deficiency, an increase in methylmalonic acid occurs, which is thought to result in loss of myelin in the peripheral nerves and, consequently, neuropathy, which may be symptomatic as early as 2 years into metformin treatment

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