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Nat Chem Biol

Lactate promotes glutamine uptake and metabolism in oxidative cancer cells

Common features of this dysfunction include impaired oxidative phosphorylation, increased ROS production, mitochondrial DNA damage, and altered organelle dynamics

Keep in mind that MTHFR variants are common: My final point is that the MTHFR C677T and A1298C variants are very common

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5H), indicating that the protein cargo sorting was affected by the inhibition of the cytoskeletal remodeling