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doi: 10.1038/s41582-019-0184-2

& Alonso, S

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Immunomodulatory Activity The thymus and spleen serve as critical central and peripheral immune organs in animals, playing essential roles in mediating both cellular and humoral immunity

Also, citrate acts as the substrate for the NADP+ dependent enzyme isocitrate dehydrogenase
: Therapeutic peptides: Current applications and future directions
