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Liver illnesses accounted for 2.2% of all fatalities worldwide in 2016, ranking as the 11th highest cause of mortality and the 15th greatest source of morbidity globally

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In IPF, antifibrotic agents have been shown to reduce the functional decline associated with the disease

IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor

These side effects are usually mild and typically go away within a few days