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Researchers identified a flavonoid called rutin as contributing to this effect
doi: 10.1038/nchembio.2239 44 LapaquettePTerratSProukhnitzkyLMartineLGrgoireSButeauBet al
At neutral to alkaline pH (above 7), deamidation proceeds through a cyclic imide intermediate that produces a mixture of normal and isomerized products
10.1016/j.jhazmat.2008.07.131 161 VerstraetenI
The blood samples were collected into polypropylene microcentrifuge tubes and cooled on ice for not more than 1 hour
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