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Anti-inflammatory and antioxidative effects of vitamin E may be explained by suppressing nuclear factor-kappa B (NF-B) and JAK-signal transducer and activator of transcription 6 (STAT6) or JAK-STAT3 signaling pathways 37

Abbreviations: RCT, randomized controlled trial

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However, their specific roles in macrophage function, particularly in the context of immune regulation, remain elusive
Results vary by individual, and no specific outcomes are guaranteed
