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When oxidative stress persists or overwhelms antioxidant defences, it can lead to cell death through both apoptosis and necrosis, as well as inflammation, aging, and various diseases such as atherosclerosis, cancer, diabetes, rheumatoid arthritis, post-ischaemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke, septic shock, and other degenerative diseases in humans [9,10,17,20,21]

doi: 10.1371/journal.pone.0049257 Han J, and Kaufman RJ ( 2016 )

doi: 10.5888/pcd12.150006

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