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Patients with underlying medical conditions, especially kidney or liver disease, should use it under medical supervision as dosage adjustments might be necessary

Martin, T

10.1007/s10337-014-2787-5 120 ZeisbergM.NeilsonE

Acute Phase Response Within minutes of tissue injury, activation of the innate immune system induces cytokine production that results in a multisystem acute phase response involving the liver, vascular system, bone marrow, and central nervous system

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delayed phase imaging reveals characteristic intense hyperenhancement of the lesion ( arrow )