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EFSA scientific opinions from 2022 to 2025 have established ADI values for multiple compounds: curcumin (3 mg/kg body weight) (243), resveratrol (150 mg/day maximum), and tetrahydrocurcuminoids (2 mg/kg body weight)

doi:10.1046/j.1524-475X.1994.20406.x

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For the diet-induced thermogenesis test, 24-week-old mice were fasted overnight for 18 h