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These findings suggest that AS-IV exerts synergistic neuroprotective effects at the multicellular level by simultaneously targeting the JNK apoptotic pathway and the NLRP3 inflammatory pathway ( Another study demonstrated that atractylenolide-I (ATR-I), the primary active component of Atractylodes macrocephala Koidz., exhibits significant neuroprotective effects in PD models

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Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation

Participants received either placebo or GW501516 (2.5 mg or 10 mg) for two weeks