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PLoS One 11 , e0165638 (2016)

In HFD-induced obese animals, critical organs, such as the heart and kidney, are closely associated with elevated oxidative stress, as indicated by reduced levels of GSH, antioxidant enzymes such as glutathione peroxidase (GPx) and catalase (CAT), and elevated levels of malondialdehyde (MDA) and protein carbonyls (16)