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Drugs 18 (12), 634

In contrast, deletion or inhibition of GPX4 causes rapid H 2 O 2 accumulation and RIPK3-mediated necrosome activation 72,73

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Niraparib showed promising activity in preclinical models and phase I clinical trials, achieving its pharmacodynamic target for PARP inhibition in epithelial ovarian cancer, particularly in patients who have responded to platinum-based chemotherapy 167 (Fig

Cox analysis was used to identify the risk factors of 1-year survival, and SOD and GR in different types of variables were included

Dedicated glycosyltransferases transfer the sugars, in their thermodynamically activated form of NDP-sugars, to nucleophiles present in natural products, most commonly alcohols