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Description
A charge gradient directs superoxide anion towards the active site since 89% of the exposed surface is negatively charged, whereas the active site and the channel leading to it are positively charged
Science 284 (5422), 19982003
E.Vande WoudeG
10.1515/chem-2022-0204 Open Chem
Their size ranges from 1-3 mm, distinguishing them from CALMs
We further validated the ubiquitination of PPAR by NEDD4
