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Eur J Med Chem (2021) 226:113839

Birringer M

The imaging was performed using the High content imager CX7 (Thermo Fisher) with a HCS Studio 4.0 software, and phenotyping and quantifications were performed using ImageJ v1.53 or CellProfiler v3 softwares

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Effect of treatment with abemaciclib and irradiation on the concentration of CK18, COX2, IL-6, and IL-1 in the cell lysate of MCF-7 and MDA-MB-231 cell lines Figure 6 demonstrates that regarding the untreated cells of each cell line, abemaciclib significantly reduced the levels of CK18, COX2, IL-6, and IL-1 in the cell lysate of MCF-7 and MDA-MB-231

6) which has two cysteine residues not involved in S-S formation