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Topical capsaicin is applied to the upper abdomen and may reduce the need for antiemetics.127129 Capsaicin may cause redirection of blood flow from the enteric system to the skin, leading to activation of TRPV1 receptors and reducing substance P.130 A randomized clinical trial examined topical capsaicin (0.1%) versus placebo cream applied to the abdomen and the authors reported a 46% reduction in nausea from the baseline in the capsaicin arm versus 24.9% in the placebo arm

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Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: a 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens

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They have reported choline chloride and LC co-administration has beneficial effects on SCC and reproductive indices, and that is better than individual LC supplementation [21]

Additionally, the diversity of the populations studied, such as variations in demographic characteristics and underlying health conditions, contributed to the heterogeneity observed