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doi: 10.6065/apem.2142210.105

Most published data comes from in vitro and animal studies

Cerebral blood flow autoregulation and dysautoregulation

BPC-157's anti-inflammatory and cytoprotective effects prove particularly valuable early, while TB-500's cell migration and angiogenic promotion become increasingly important as repair progresses

In vitro mechanistic studies also showed that the lead compound C1-27 acts as a slow-turnover substrate, though the significance of this mechanism is currently unclear

Moreover, the in vivo findings confirmed that therapy with AuNPs effectively avoided neuroinflammation in dopaminergic neurons and elevated dopamine levels