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The mechanisms include blood pressure reduction, improvement in lipid profiles, anti-inflammatory effects on the arterial wall, and possible direct cardioprotective effects through GLP-1R expressed on cardiomyocytes

Specific clinical scenarios where injections are the standard of care include pernicious anemia, severe malabsorption syndromes, post-bariatric surgery when oral supplementation has failed, and critically low serum B12 levels accompanied by neurological deterioration

Vitamin B12 is important for health, and nitrous oxide use can result in damage to your nervous system

With the compounded medications, splitting doses was possible because the compounding pharmacies presented the GLP1s in multi-dose vials which included a preservative to maintain its effectiveness over time

NNMT stands for nicotinamide N-methyltransferase

If you eat a well-balanced diet that includes foods rich in vitamin B12, then it is unlikely that youll need to take additional B12