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doi: 10.3389/ftox.2024.1376587 Received 25 January 2024 Accepted 01 July 2024 Published 12 August 2024 Volume 6 - 2024 Edited by Marcelo Dutra Arbo, Federal University of Rio Grande do Sul, Brazil Reviewed by Stacy Matthews Branch, Independent Researcher, Sarasota, FL, United States Peter Bonitatibus, Rensselaer Polytechnic Institute, United States Updates Copyright 2024 Cunningham, Kirk, Hong, Yang, Howard, Brearley, Senz-Trevizo, Krawchuck, Watt, Henderson, Dokladny, DeAguero, Escobar and Wagner

Comparative features of sarin (GB), soman (GD), and VX are summarized with respect to persistence, odor, and primary exposure route

It operates on the whole body, not just one part

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

Kurutas et al., 2005

These include one or more of the following: Loss of consciousness, syncope, dizziness, or lightheadedness at any time Systolic blood pressure less than 90 mm Hg, Glasgow Coma Scale score less than 15 (related to cardiovascular system collapse and/or neurologic dysfunction from hypoperfusion, hypoxia) Dyspnea, wheeze, hoarseness, or bronchospasm Stridor, cyanosis, laryngeal edema, or a respiratory rate 25/min Manifestations of anaphylaxis involving the cutaneous, gastrointestinal, and respiratory organs tend to worsen with each grade and have implications for treatment and life support