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This dichotomy highlights the fact that the net biological outcome of the phytochemicals is dictated by the ratio between pathway inhibition in the diseased cells and maintenance of Wnt activity in normal tissues [66], [343])
In turn, presence of -secretase inhibitors in these cell lines abrogates the -secretase-dependent activation of the non-amyloidogenic pathway by melatonin [52]
Silymarin and celecoxib ameliorate experimental varicocele-induced pathogenesis: evidences for oxidative stress and inflammation inhibition
