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Activation of p53 by MDM2-inhibition sensitizes quiescent blast crisis CML stem/progenitor cells to Bcl-2 inhibitor- and tyrosine kinase inhibitor-induced cell death

Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]

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Transplanting embryonic stem cell-derived astrocytes into murine ALS models with the SODG93A mutation has been found to restore young astrocyte characteristics, potentially slowing disease progression 131

Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen)