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Castaneda, M

Undermining glutaminolysis bolsters chemotherapy while NRF2 promotes chemoresistance in KRAS-driven pancreatic cancers

The level of GSH is strictly controlled by either substrate availability or transcriptional regulation of specific gene (Petersen Shay et al., 2008)

Prolyl-4-hydroxylases 2 and 3 control erythropoietin production in renin-expressing cells of mouse kidneys

therefore, researchers warn that it carries the identical theoretical risk of exacerbating oncological conditions by promoting new blood vessel formation within tumor microenvironments, rendering it unsafe for use in patients with a history of cancer

Furthermore, its ability to stimulate neurogenesis and control synaptic plasticity may hold promise for improving cognition