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It works by reducing melanin productionthe pigment responsible for darker skin

Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative lc-ms analysis of therapeutic antibodies in the cerebrospinal fluid

DOI: 10.1373/clinchem.2005.061408 19

Another significant metformin side effect: vitamin B12 deficiency

Deficiency can cause fatigue, nerve issues, and memory problems
Paraffin sections were immunohistochemically stained using standard procedures
