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2013 Sep 15;591(18):4655-66

A recent study suggested that plasma levels of 5-MT, a compound related to serotonin metabolism, may be decreased in CFS patients, but this has been interpreted as a confounder caused by serotonin-selective reuptake inhibitor (SSRI) use in these patients ( The principal role of carnitine is to transport long-chain fatty acids into the mitochondria for energy production via beta-oxidation (53)

Schep et al., 2010

That's part of the story but acetyl-L-carnitine (ALCAR) is doing something standard L-carnitine can't

Clinical trials have demonstrated that 6-week oxaloacetate supplementation produces marked improvements in both physical and mental fatigue
