melanotic macule size macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Oral melanoacanthoma and oral melanotic
Description
Relation to the effect of dexamethasone in soleus muscle and spleen

POMC is proteolytically cleaved to its products, alpha melanocyte stimulating hormone (-MSH) and adrenocorticotropin hormone (ACTH), which are secreted by keratinocytes and bind the melanocortin 1 (MC1R) on melanocyte membranes

Retrieved 17 May 2021

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This is precisely where sexual desire and arousal originate neurologically
