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The female-specific model strengthens the novelty of the work by expanding current evidence beyond male-centered studies and by providing a basis for future investigations testing whether hormonal status (e.g., estrous cycle phase, ovariectomy, or menopause-like models) modifies ECS regulation and responses to full-spectrum cannabinoid preparations in MASLD (37, 38)

10.1016/j.jnutbio.2018.01.005 [DOI] [PMC free article] [PubMed] [Google Scholar] Wang Y., Zhang L., Li H

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doi: 10.1002/lt.25443