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Examining the association between vitamin B12 deficiency and dementia in high-risk hospitalized patients

For example, overexpression of the BRCP/ABCG2 transporter is associated with resistance to several anti-cancer drugs including doxorubicin, mitoxantrone and topotecan [65], whilst ABCB1/MDR1 is frequently overexpressed in drug-resistant cell lines and is found to correlate with poor overall survival in patients [20, 66]

Interactions with other medications appear minimal based on available data, but comprehensive medication review is essential before starting BPC-157

Curr Treat Options Oncol

Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation