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The 50100mg daily dose range was derived from rodent models where 10mg/kg bodyweight produced measurable NNMT suppression without toxicity across 12-week administration periods

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It might feel a little intimidating at first, but following a clear process makes all the difference

Timelines vary by tissue: gut symptoms often improve in 2 to 4 weeks, while tendon and ligament changes typically take 3 to 4 weeks to begin and longer to consolidate

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Wegovy summary of product characteristics