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However, additional randomized clinical studies are needed to define its effectiveness in this setting

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Kruse MN, et al

A., Dwyer, P

(2019) Do non-steroidal anti-inflammatory drugs cause osteoarthritis progression, a systematic review and meta analysis

Researchers at the University of Zagreb first isolated and characterized this compound in 1993, initiating decades of preclinical investigation

doi: 10.1038/s41467-020-15174-3
