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doi: 10.1016/j.lfs.2020.118356 23

Macular ganglion cell-inner plexiform layer thickness for detection of early retinal toxicity of hydroxychloroquine

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Renal impairment affects not only the renal excretion of a drug but may also alter metabolism and active transport in the kidney, liver or gut and affect absorption, tissue distribution and plasma protein binding [13]

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High levels of MMA disrupt normal fatty acid synthesis, forcing the body to incorporate abnormal fatty acids into neuronal lipids
