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Description
Compared to Oral administration, whereby under 10% actually enters the blood stream, Oro-buccal administration by Oral Dispersible Film(ODF) leads to over 80% absorption directly into the systemic circulation
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Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional overdose of acetaminophen (APAP) has affected patients for decades, and involves the cornerstone metabolic pathways which take place in the microsomes within hepatocytes
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