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Revealed in various studies, numerous nanomaterials have demonstrated the capability to induce ferroptosis by depleting GSH

De Barros Moreira Filho AL, De Oliveira CJ, De Oliveira HB, Campos DB, Guerra RR, Costa FG, Givisiez PE

Its effects are not exclusive to joint health either

Proc Natl Acad Sci U S A 101:74277432

ROS-associated tumor immunity in cellular immunotherapy In the field of cellular immunotherapy, especially with therapies represented by CAR-T and CAR-NK cells, the redox state of the TME is a key obstacle determining their efficacy

PC2 shares 49% amino-acid identity with Kex2, but importantly lacks its transmembrane (TM) segment, indicating that it was likely to be a soluble protease and thus was a candidate for one of the processing endoproteases in -cell secretory vesicles