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[PubMed] [Google Scholar] 31.Pflaum Z., Rucman R
The compound a 15-amino-acid pentadecapeptide originally isolated from human gastric juice demonstrates unusual protease resistance combined with angiogenic and anti-inflammatory signaling
In December 2024, the FDA's Pharmacy Compounding Advisory Committee declined to include it on the 503A bulk drug substances list, meaning compounding pharmacies in the United States cannot legally produce it for individual prescriptions
Nicotinamide mononucleotide (NMN) was excluded from the dietary supplement definition by FDA in 2022-2023 and remains in regulatory limbo for new dietary supplement marketing in the US
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