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Real-time quantitative PCR analysis Total RNA was extracted using TRIzol (Invitrogen, USA), and then a NanoDrop-2000 (Thermo Fisher, USA) was used to measure the concentration of total RNA for reverse transcription

Eur Heart J 1994;15:1267-73

doi: 10.1182/blood-2006-08-042531

Both GSH and SB431542 significantly down-regulated the TGF1/SMAD pathway and the expression of -SMA under high glucose conditions (Fig

10.1016/j.cbpa.2010.11.012 82 LessmeierL.HoefenerM.WendischV

It is worth noting here that the Lp(a) molecule has a high homology (7599%) with plasminogen, but lacks protease activity, and was therefore assumed to inhibit fibrinolysis and show prothrombotic potential [33], but this has not been confirmed by recent studies on the effect of lowering Lp(a) on fibrinolytic activity or by studies on the effect of elevated Lp(a) levels on venous thrombosis [7, 8]