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This includes: The S0 category prohibits any pharmacological substance with no current approval by any governmental regulatory health authority for human therapeutic use
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J Neuropathol Exp Neurol 2011;70:979-91

In general, by either excess or impairment, NO appears to cause or contribute to a variety of disturbances, in particular, hypertension, angina, impotence, circulatory shock, septic shock, stroke, inflammation, respiratory distress syndromes, pulmonary hypertension, adhesion and aggregation of platelets and leukocytes, diabetes, hypotension, and Parkinson's disease

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