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However, there are also some limitations, including the difference in the shape of respective nasal cavities, the exact dosing of intranasal drugs, the mucociliary elimination, and the drainage to the pharynx or to the lower part

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338 However, in heart failure, DEAD-box helicase 17 and B-cell lymphoma 6 are downregulated, which would reverse the inhibition of Drp1 and promote mitochondrial fission

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