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The chronic use of any of these medications has the potential to cause complications related to vitamin B12 deficiency, which includes impaired DNA synthesis, impaired cell division, hematopoiesis, hyperhomocysteinemia, and metabolism of odd-chain fatty acids that is necessary in preventing demyelination of nerves

Overall, however, the preclinical evidence for a benefit of NAC in the context of lung cancer is mixed

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The recommended dosage is 5 mg a day, increasing to 25 mg over one or two weeks

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