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Haematologica 102 (3), 454465

SOD, in turn, catalyzes the conversion of the superoxide anion (O 2 ) into H 2 O 2 , which is subsequently detoxified

Depletion of mitochondrial methionine adenosyltransferase 1 triggers mitochondrial dysfunction in alcohol-associated liver disease

Interestingly, recent studies indicate that in the setting of ATII-induced hypertension, a downregulation of the dihydrofolate reductase was observed, which was accompanied by decreased vascular BH 4 levels and an uncoupled eNOS, 91 implicating a potential role of this salvage pathway in the development of hypertension

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They pretreated subjects with n-acetyl-cysteine infusion (150 mgkg -1 ) or a 5% dextrose placebo while undergoing an extended fatiguing bout of electrical stimulation of the ankle dorsiflexors