glutathione t cells car Metabolic engineering for optimized CAR-T cell therapy A genome-scale gain-of-function CRISPR screen
Description
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GGT allows hydrolysis of a broad range of -glutamyl amides and transpeptidation of amino acids or dipeptides [32]
The concentration of produced ammonia was detected using an Ammonia Assay Kit (Abcam, Cambridge, UK) according to the manufacturers instructions
By disrupting the cellular membrane, free radicals can also break down peptide bonds, oxidize amino acids, as well as cause lipid peroxidation
However, in p53 wild-type glioblastoma, p62 attenuates ferroptosis and promotes SLC7A11 expression
