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Generally, CSF CRP can be useful in discriminating between bacterial and viral CNS infections, and it has been connected to aggression in personality-disordered individuals [603,604,605,606,607]
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It emerged as a distinct cell death program due to the activation of caspase 1 and caspase 11-dependent inflammasomes in macrophages infected with Salmonella [116, 117]

They are critically important within the context of the brain and the kidney
