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While the shift to address the underlying drivers of NASH holds promise, many of the mechanisms under investigation are limited to the liver as their site of action, because of safety constraints arising from systemic exposure ( Table 1 )

These metabolites may be involved with the development of glaucomatous pathophysiology

Other acute or chronic hepatopathies

The WHO bacterial priority pathogens list 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance

Mastrogiacomo, LaMarche J, Do S, Lindsay G, Bettendorff L, et al