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Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Stadel JM, Strulovici B, Nambi P, Lavin TN, Briggs MM, Caron MG, Lefkowitz RJ

Inhibition of Autophagy Kinase ULK1 Combined with Chemotherapy Results in Modulation of Reactive Oxygen Species and DNA Damage Response to Induce Synergistic Cell Death in Acute Myeloid Leukemia

Peripheral blood mononuclear cells (PBMC) and leukemic THP-1 cell viability can be affected by aqueous root extracts of WS (0.050.4 mg/ml), which can also increase oxidant scavenging and caspase [99, 100] activities while decreasing levels of tumor necrosis factor-alpha (TNF-), interleukin (IL)10, and glutathione (GSH) [112]
A CTNNB1-altered medulloblastoma shows the immunophenotypic, DNA methylation and transcriptomic profiles of SHH-activated, and not WNT-activated, medulloblastoma
