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Sulforaphane alleviates ethanol-mediated central inhibition and reverses chronic stress-induced aggravation of acute alcoholism via targeting Nrf2-regulated catalase expression

This ideally positioned melatonin as a radical scavenger since the process of oxidative phosphorylation in mitochondria is the site of the production of the superoxide anion radical, the precursor of all other destructive ROS as well as reactive nitrogen species (RNS) ( Figure 3 )

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These famous antioxidants complement Glutathione by helping to neutralize free radicals